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When President Obama signed the Family Smoking Prevention and Tobacco Control Act in 2009, it gave government regulators an important new weapon in its battle against Big Tobacco.

For the first time, the Food and Drug Administration had the power to regulate the manufacturing, distribution and marketing of tobacco products, including the new and then-largely unknown practice of vaping.

Officials at the Centers for Disease Control and Prevention say there has been a breakthrough in the investigation into the outbreak of vaping-related lung injuries that has led to the deaths of 39 people and sickened more than 2,000 others.

Investigators announced Friday that they have detected a chemical compound called vitamin E acetate in all the samples of lung fluid collected from 29 patients who were hospitalized after vaping, suggesting a possible culprit for the spate of lung injuries that has swept across the U.S.

Two major retailers say they will no longer sell e-cigarettes and related products in the U.S. amid mounting health questions surrounding vaping. 

Updated at 1:01 p.m. ET

Juul Labs has agreed to stop advertising its popular e-cigarettes in the United States and announced that its chief executive officer is stepping down as state and federal regulators examine hundreds of cases of people who are sick from what appears to be a vaping-related lung disease.

Nationwide, people who vape continue to sicken with severe and unexplained lung illness, leaving doctors and patients concerned about both the acute and long-term effects of the injuries.

The Centers for Disease Control and Prevention announced Thursday that there are now 530 confirmed or probable cases of lung injury associated with vaping, a jump from 380 cases reported last week. Seven people have died.